Clearmind Medicine (Nasdaq:CMND) Expands Global AUD Study with First Israeli Patient

VANCOUVER, Canada — November 25, 2025 — Leads & Copy — Clearmind Medicine Inc. (Nasdaq: CMND), a clinical-stage biotech company, has announced the recruitment of the first patient at Tel Aviv Sourasky Medical Center (TASMC) in Israel for its Phase I/IIa clinical trial of CMND-100 in Alcohol Use Disorder (AUD).

TASMC, a leading medical center in Israel, joins an expanding global network of trial sites that includes Yale School of Medicine, Johns Hopkins University School of Medicine, and Hadassah Medical Center.

The Phase I/IIa trial is designed to assess the safety, tolerability, pharmacokinetics, and preliminary efficacy of CMND-100, Clearmind’s non-hallucinogenic, oral MEAI-based compound.

Recent top-line results from the first completed cohort of the trial indicated excellent safety and adherence, with no serious adverse events reported.

Prof. David Zeltser, Director of Internal Medicine Department and Deputy Director, R&D and Innovation at TASMC, is the principal investigator at the Israeli site.

According to Dr. Adi Zuloff-Shani, CEO of Clearmind Medicine, the recruitment of the first patient at TASMC marks a significant advancement for the global trial and brings CMND-100 closer to potentially transforming AUD treatment.

Clearmind Medicine Inc. is focused on discovering and developing novel neuroplastogen-derived therapeutics to solve major under-treated health problems, with a primary objective to research and develop psychedelic-based compounds for commercialization as regulated medicines, foods or supplements.

The company’s intellectual property portfolio consists of nineteen patent families, including 31 granted patents, and Clearmind intends to pursue additional patents and acquire further intellectual property as warranted.

Clearmind shares are traded on Nasdaq under the symbol “CMND” and on the Frankfurt Stock Exchange under the symbol “CWY0.”

Investor Relations: invest@clearmindmedicine.com, Telephone: (604) 260-1566. US: CMND@crescendo-ir.com. General Inquiries: Info@Clearmindmedicine.com.

Source: Clearmind Medicine Inc.

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